- Adults with IBD are at higher risk for fibromyalgia than adults without IBD, according to a large Taiwanese retrospective cohort study.
- Male and younger patients (ages 20-39 years) with IBD face the highest risks.
Why this matters
- IBD patients should be screened for fibromyalgia and referred for diagnosis and treatment.
- Retrospective, population-based, cohort study, 1 million medical records, Taiwan National Health Insurance Research Database.
- 4510 patients with newly diagnosed IBD (from 2000 to 2005) and without fibromyalgia were followed for 12 years and compared with 18,040 controls (sex-, age-matched) without IBD.
- Results adjusted for comorbidities, including hypertension, diabetes, hyperlipidemia, depression, anxiety, sleep disorder.
- Funding: Taiwan Ministry of Health and Welfare; China Medical University Hospital; Ministry of Education, Taiwan; NRPB Stroke Clinical Trial Consortium.
- With IBD, risk for fibromyalgia (adjusted HRs):
- Versus controls: 1.70 (95% CI, 1.59-1.83).
- In men: 2.00 (95% CI, 1.79-2.23).
- In women: 1.52 (95% CI, 1.38-1.67).
- By age, highest in youngest age group studied (ages 20-39 years): 1.92 (95% CI, 1.68-2.19).
- Some cardiovascular comorbidities could not be studied.
- Retrospective design.