IBD: peripheral arthritis or spondyloarthritis found to be common in IBSEN

  • Ossum AM & al.
  • Scand J Gastroenterol
  • 24 Oct 2018

  • curated by Miriam Davis, PhD
  • Clinical Essentials
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Takeaway

  • 17.2% of patients with inflammatory bowel disease (IBD) develop IBD-related peripheral arthritis (PA), and 27.9% develop a related rheumatological disorder, peripheral spondyloarthritis (pSpA), at 20 years after diagnosis, according to a large, prospective cohort study.

Why this matters

  • Patients with long-term IBD should be screened for PA and pSpA.

Study design

  • Population-based prospective cohort of newly diagnosed patients with IBD evaluated by questionnaire at 20 years' follow-up (n=441) of the Inflammatory Bowel South-Eastern Norway (IBSEN) study.
  • IBD-related PA was defined as peripheral arthritis not explained by other specific diagnoses.
  • pSpA was defined by the criteria of the Assessment of Spondyloarthritis International Society, which included peripheral arthritis, enthesitis, and/or dactylitis.
  • Funding: South-Eastern Norway Regional Health Authority.

Key results

  • The prevalence of IBD-related PA was 17.2%, and that for pSpA was 27.9%, neither of which varied by IBD diagnosis (ulcerative colitis vs Crohn's disease).
  • IBD-related PA and pSpA were more common in female patients with IBD (67.1% and 61.8%, respectively, vs 46.4% in those without the condition; each P<.01>
  • Patients with IBD-related PA or pSpA had no greater IBD severity or activity than control patients without these conditions.

Limitations

  • No radiographic confirmation of PA or pSpA.
  • Self-report with potential for recall bias.

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