IBS linked to inflammation-promoting foods

  • Salari-Moghaddam A & al.
  • Nutr J
  • 11 Nov 2019

  • International Clinical Digest
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Takeaway

  • Pro-inflammatory diet is associated with an increased risk of inflammatory bowel syndrome (IBS), particularly among women and patients with BMI ≥25 kg/m2.

Why this matters

  • Consuming foods with lower dietary inflammatory index (DII) scores may prevent IBS in some patients.

Study design

  • Researchers studied dietary intake and IBS status of participants (n=3363) who responded to a validated, dish-based, semiquantitative food frequency questionnaire (DS-FFQ) and a modified Rome III diagnostic questionnaire for functional gastrointestinal disorders.
  • They used DS-FFQ data to classify participants into DII score quintiles.
  • Funding: Tehran University of Medical Sciences.

Key results

  • Top DII quintile participants were more likely to develop IBS than those in the bottom quintile (OR, 1.36; 95% CI, 1.03-1.80).
  • This association was greater for top DII quintile women than men (OR, 1.41; 95% CI, 1.00-2.00).
  • Top DII quintile participants with BMI ≥25 kg/m2 were more likely to develop IBS than those in the bottom quintile (OR, 1.64; 95% CI, 1.07-2.53).
  • DII score was not significantly associated with IBS symptom severity.

Limitations

  • The study was cross-sectional and did not establish causality.
  • Participant diet and health data were self-reported.
  • Participants were Iranian health workers; findings may not apply to other populations.