A new analysis has found rates for all types of kidney replacement therapy (KRT) in European countries have been consistently higher in men than women over the past five decades.
For the study, researchers analysed data from nine countries reporting to the European Renal Association-European Dialysis and Transplant Association (ERA-EDTA) Registry during 1965 to 2015 to examine sex differences in KRT over time. Data from 230,378 patients receiving KRT were included, of whom 89,132 were women.
Although more women than men are affected by chronic kidney disease, the authors found the incidence and prevalence rates for all KRT modalities were consistently higher in men. Furthermore, the authors noted male-to-female ratios, calculated for incident and prevalent KRT patients, increased with age, showing consistency over decades and for individual countries, despite marked changes in primary kidney disease. They also reported that the male-to-female ratio was higher for kidney transplantation in diabetic patients.
The authors say more research is needed to better understand whether the findings are related to biology, access to care or other reasons.
The research is published in the Clinical Journal of American Society of Nephrology (CJASN).