The largest ever UK lung cancer screening project has been launched. The SUMMIT study, which is supported by NIHR University College London Hospitals Biomedical Research Centre, will support the development of a new blood test for the early detection of multiple cancer types, including lung cancer.
The study aims to recruit approximately 50,000 men and women aged 50-77 years from north and east London. Half of the participants will be people at high risk for lung and other cancers due to a significant smoking history, and the other half will be people who are not at high risk for cancer based on smoking history.
All participants will provide a blood sample for genomic testing. Participants at high risk for lung cancer will also be screened using low-dose CT scan.
The study, which will begin in early 2019, is expected to provide evidence to inform a potential national lung cancer screening programme.
Prof Geoff Bellingan, Medical Director for cancer and surgery at University College London Hospitals and professor of intensive care medicine at University College London, said: “The SUMMIT study is the largest lung screening programme in the United Kingdom. It provides us with a once-in-a-lifetime opportunity to change how lung cancer is diagnosed - both by paving the way for a national screening programme here in the United Kingdom and supporting global efforts to develop a novel blood test for early detection of multiple cancers, including lung cancer.”