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The risk for cardiovascular events linked to apolipoprotein B (apoB) particles decreases with age, underscoring the importance of therapy to lower low-density lipoprotein (LDL) levels for younger patients with elevated lipids.
Why this matters
High concentrations of the apoB lipoproteins increase the risk for cardiovascular disease.
Researchers determined the associations for total cholesterol, LDL‐cholesterol (LDL-C), non‐high‐density lipoprotein‐cholesterol (non‐HDL‐C), apoB, apolipoprotein A‐I (apoA‐I), and HDL‐C with myocardial infarction (MI) at different ages (11,760 control patients, 8998 patients with myocardial infarction [MI]).
They then used logistic regression to compute the MI OR for 1 SD change in each lipid marker by decade from <40 to >70 y of age.