- A moderate-fat diet high in unsaturated fats offered some modest cardiovascular (CV) benefits in this study , although the authors found no decrease in systolic BP, and "good" cholesterol decreased.
- The authors evaluated the effects of walnuts as a whole food, fatty acids (FAs) found in walnuts, and other FAs.
Why this matters
- The authors say that their findings suggest that FAs (from vegetable oils or walnuts) are a healthy replacement for saturated FAs in the diet.
- The unsaturated FA diets did not affect central systolic BP.
- Arterial stiffness was also unaffected.
- Walnuts in the diet were linked to a reduction in central diastolic BP vs 1 FA diet (P=.04), but otherwise the various diets did not differ for this outcome.
- All of the diets were linked to reductions in all cholesterol measures, including high-density lipoprotein (HDL) cholesterol.
- There were no differences among the diets for lipid, glucose, or insulin measures.
- Randomized, controlled, 3‐period, crossover, feeding trial, 45 people (36 completers).
- 3 diet groups: walnuts added, walnut FAs added, or oleic acid-replaced FA diet.
- Funding: California Walnut Commission; NIH.
- Very small study.
- Primary endpoint not met.