- Incidence rates for myeloid cancers and chronic lymphocytic leukemia (CLL) have increased sharply among baby boomers, correlating strongly with population aging.
Why this matters
- The entire baby boomer generation will be aged ≥65 years by 2030.
- Incidences of myeloid leukemia and CLL significantly outpaced that of cancer overall.
- Analysis of changes in cancer incidence in the United States, 1998-2018.
- Data source: American Cancer Society.
- Funding: National Institutes of Health; City of Hope Center for Cancer and Aging.
- Population-adjusted incidences for leukemia in 1998 vs 2018 (cases/incidences per 100,000):
- 19% increase in all-cancer incidence: 445.3 vs 531.1.
- 78% increase in leukemia incidence: 10.4 vs 18.5.
- Significant correlations between cancer incidence and population aging for years 1999 (when baby boomers began to turn 65 years) through 2011:
- All cancers: Pearson r=0.90; P<.0001.>
- CLL: Pearson r=0.77; P=.0022.
- Acute lymphocytic leukemia: Pearson r=0.85; P=.0003.
- Chronic myeloid leukemia (CML): Pearson r=0.94; P=.0004.
- Acute myeloid leukemia (AML): Pearson r=0.84; P=.0082.
- CLL: Pearson r=0.84; P=.0094.
- Data source did not distinguish between therapy-related and de novo AML.