- Adults with neurodevelopmental disabilities (NDDs) have approximately double the risk of fracture vs adults without NDDs.
- Increasing comorbidity of NDDs is associated with even higher prevalence of fractures at most anatomical locations.
Why this matters
- Findings from this neglected population suggest the need for earlier screening and preventive interventions for musculoskeletal frailty.
- Retrospective cohort of 3 common NDDs: intellectual disabilities (n=69,456), autism spectrum disorders (n=21,844), and cerebral palsy (n=29,255).
- Control group was adults without NDDs (n=8.7 million).
- Because risk of fracture increases with age, all prevalence figures were age-standardised.
- Funding: University of Michigan.
- NDD adults had approximately double the rate of any fracture vs non-NDD adults:
- Women: 8.3% with intellectual disabilities, 8.1% with autism spectrum disorders, and 8.5% for cerebral palsy vs 3.5% with non-NDD.
- Men: 6.6% with intellectual disabilities, 5.9% with autism spectrum disorders, and 6.7% for cerebral palsy vs 3.0% with non-NDD.
- Increasing comorbidity of NDDs was associated with higher prevalence of any fracture: 1 NDD (women, 7.7%; men, 5.7%), 2 NDDs (9.4%; 7.2%, respectively), 3 NDDs (11.3%; 13.7%, respectively).
- Reliance on administrative data claims.