New guidelines for hyperthyroidism

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Takeaway

  • The American Thyroid Association (ATA) has released updated guidelines on the diagnosis and treatment of hyperthyroidism and other causes of thyrotoxicosis, including 124 evidence-based recommendations on the basis of an extensive literature review.

Background

  • A task force of experts from North America, South America, and Europe reviewed published research on the diagnosis and treatment of thyrotoxicosis.
  • Funding: Study funded by ATA

What’s new in the guidelines

  • A revised list of the most common causes of thyrotoxicosis.
  • Evaluation of the etiology of the disease.
  • Management of Graves’ disease using antithyroid drugs.
  • Management of hyperthyroidism during pregnancy.
  • How to prepare patients for thyroid surgery.
  • Expanded sections on rare causes of the disease.

Additional topics covered

  • Initial diagnosis and management.
  • The use of radioactive iodine, antithyroid drugs, or surgery in Graves’ disease.
  • Treatment of toxic multinodular goiter or toxic adenoma with radioactive iodine or surgery.
  • Graves’ disease in children, adolescents, or pregnant patients.
  • Subclinical hyperthyroidism.
  • Hyperthyroidism in patients with Graves’ orbitopathy.
  • How to manage other causes of thyrotoxicosis.

Why this matters

  • Significant scientific advances in the field since the original guidelines were published in 2011 by the ATA and the American Association of Clinical Endocrinologists meant that some current clinical issues were not addressed.