- The rate of hospitalization for pregnancy-related acute kidney injury (Pr-AKI) has risen across all major racial/ethnic groups.
- Blacks were disproportionately affected by Pr-AKI compared with Whites and Hispanics.
Why this matters
- The rate of Pr-AKI has tripled from 1993 to 2014, but racial differences have not been studied.
- Pr-AKI is associated with multiple adverse pregnancy outcomes, including preterm labor, miscarriage, and death.
- Data were drawn from the National Inpatient Sample, the largest publicly available all-payer inpatient care database in the United States, from 2005 to 2014.
- Hospitalizations for pregnancy and Pr-AKI were determined by ICD codes.
- Logistical regression was performed for age, income, hospital type, and comorbidities.
- 7058 Pr-AKI cases were identified among 9,768,905 pregnancy hospitalizations.
- Hospitalizations for Pr-AKI rose from 0.04% of all pregnancies in 2005 to 0.12% in 2015, but from 0.07% to 0.3% over the same period for Blacks.
- Blacks accounted for 29% of patients with Pr-AKI, vs 12.4% of non-AKI patients.
- Whites: 32.6% Pr-AKI, 43.8% non-AKI.
- Hispanics: 15.8% Pr-AKI, 19.2% non-AKI (P<.0001 for effect of race>
- Pr-AKI was more common in older women, those of lower socioeconomic status, and those with comorbidities (diabetes, hypertension, obesity, anemia, pulmonary circulation disorders; all P<.0001>
- NIS database excludes some hospital types.
- Not all clinical details are captured.