- High-school students with a history of nonmedical prescription opioid use were 10%-13% more likely to subsequently use heroin than opioid-naive teenagers.
Why this matters
- This study followed teenagers for 42 months, offering the first long-term look at how illicit opioid use increases the risks of future heroin use in this population.
- Study of 3298 participants (age, 14-18 years) during 2013-2017.
- Funding: NIH.
- 2.1% of participants initiated heroin use during the follow-up period.
- Nonmedical prescription opioid use was significantly associated with subsequent heroin use initiation in the participants with:
- Prior nonmedical prescription opioid use vs no use (HR, 3.59; P<.001 and>
- Current nonmedical prescription opioid use vs no use (HR, 4.37; P<.001>
- Survey-based design.
Coauthored with Antara Ghosh, PhD