Preterm prelabour rupture of membranes may influence outcomes in the next pregnancy
Access to the full content of this site is available only to registered healthcare professionals.
Register to read more
Pregnancy preterm prelabour rupture of membranes (PPROM) in the first pregnancy is associated with significant adverse maternal and perinatal outcomes in the next pregnancy, but not reduced likelihood of second pregnancy.
Why this matters
PPROM is associated with up to 40% of preterm births, and is a leading cause of maternal, foetal and neonatal morbidity and mortality that follow.
Women with a history of PPROM (n=37,776); divided into exposed (PPROM in first pregnancy; n=1979) and unexposed (no PPROM; n=35,797) cohorts.
Pregnancy outcomes in the second singleton pregnancy assessed in each cohort (exposed, n=1174; unexposed, n=20,860)
Funding: National University Hospital, Singapore.
PPROM women in the first singleton pregnancy were at an increased risk for adverse outcomes in the next singleton pregnancy: