Psychotropic medication tied to fracture risk

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  • A large population cohort shows an increased risk for fracture in patients taking selective serotonin reuptake inhibitors (SSRIs), antipsychotics, and benzodiazepines.

Why this matters

  • The study suggests that psychotropic medication use is a risk factor for fractures.

Study design

  • The researchers analyzed data from 68,730 individuals (62,275 women; age, 40 y and older) who underwent a baseline bone mineral density assessment between January 1, 1996 and March 28, 2013. Fracture risk was assessed on March 28, 2013.
  • Funding: None disclosed.

Key results

  • 18.9% of participants had mental disorders, and 17.4% used psychotropic medications.
  • Ri...