- Women with rheumatoid arthritis (RA) may be at higher risk for several adverse pregnancy outcomes, according to an analysis of the largest inpatient database in the United States.
Why this matters
- Women with RA should have close antenatal monitoring.
- Inpatient pregnancy-related admissions were compared among women with (n=31,439) and without (n=42,286,209) RA in the US Nationwide Inpatient Sample.
- Funding: None.
- Women with RA (vs without RA) were at higher risk for:
- hypertensive disorders (13.5% vs 8.9%; aOR, 1.16; P<.001>
- premature rupture of the membranes (5.4% vs 3.4%; aOR, 1.5; P<.001>
- antepartum hemorrhage (3% vs 2%; aOR, 1.23; P<.001>
- preterm delivery (10.2% vs 6.6%; aOR, 1.46; P<.001>
- intrauterine growth retardation (3.5% vs 1.8%; aOR, 1.93; P<.001 and>
- cesarean section (35% vs 28%; aOR, 1.17; P<.001>
- Cannot determine whether outcome was primary risk of hospitalization.
- Causality cannot be inferred from analysis.