Stage 1 hypertension may predict 10-year incidence of cardiovascular disease

  • Critselis E & al.
  • J Hum Hypertens
  • 11 Feb 2019

  • curated by Sarfaroj Khan
  • UK Medical News
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A recent study found high normal blood pressure (HNBP) and stage 1 hypertension to be associated with a notable increased risk for 10-year fatal and non-fatal cardiovascular disease (CVD). The finding was published in the Journal of Human Hypertension.

This population-based, prospective cohort study enrolled 3042 participants of which 2583 participants were followed up for 10 years. Following the 10-year follow-up, 2020 participants were assessed for the incidence of non-fatal and fatal CVD. Participants were classified into the following groups: (a) HNBP (systolic BP [SBP], 120-139 mmHg and diastolic BP [DBP], 80-89 mmHg) and no prior history of high BP (b) Elevated BP (SBP, 120-129 mmHg and DBP,

At baseline, the prevalence rate of HNBP, elevated BP and stage 1 hypertension was 44.6%, 29.0% and 15.5%, respectively. During the follow-up period, the 10-year combined (fatal or non-fatal) CVD incidence rates in patients with HNBP, elevated BP and stage 1 hypertension were 15.6%, 12.0% and 22.5%, respectively, vs 6.3% in normotensives (P<.0001 for all after adjustment confounders patients with hnbp had a fold hr ci increased risk cvd events vs normotensive individuals. similarly stage hypertension were at particularly in men elevated bp did not show difference the>

Authors commented, “Considering the notable increased risk for 10-year fatal and non-fatal CVD with HNBP and stage 1 hypertension, targeted primary and secondary prevention interventions are required particularly among HNBP and stage 1 hypertension individuals to prevent CVD and related adverse health outcomes.”

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