New research suggests statins are linked with an increased risk of diabetes and with skin and soft tissue infections (SSTIs).
As part of a new study, researchers performed a sequence symmetry analysis (SSA) on prescription claims from the Australian Department of Veterans’ Affairs between 2001 and 2011 to investigate the link between statin use with SSTIs and diabetes and whether diabetic patients were susceptible to SSTIs.
They found statin use over as little as 91 days was associated with a significant risk of SSTIs. Statins were also linked with a significant risk of new-onset diabetes, the authors said. The increased risk of infection was seen in individuals who did and did not develop diabetes. The authors said the risk was unbiased by socio-economic statuses.
Writing in the British Journal of Clinical Pharmacology, the authors said further research is now needed in this area. “Regardless of the actual mechanism(s), it would seem prudent for clinicians to monitor blood glucose levels of statin users who are predisposed to diabetes, and be mindful of possible increased SSTI risks in such patients,” the authors concluded.