Tubal ligation is not associated with early natural menopause

  • Obstet Gynecol

  • International Clinical Digest
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • Surgical sterilization is not associated with risk for early menopause.

Why this matters

  • Surgical sterilization, through tubal occlusion or salpingectomy, is one of the most common methods of contraception in the United States.
  • Tubal ligation is associated with a decreased risk for ovarian cancer, which led to a suspicion of a long-term effect on ovarian function.

Key results

  • Mean age of natural menopause was 50.0 years.
  • No difference in age of natural menopause in women with tubal ligation compared with those without tubal ligation.
  • Type of surgical procedure did not affect age at menopause.

Study design

  • Cross-sectional study using 3 preexisting cohorts:
    • Cohort 1: women with history of oophorectomy prior to age 50 years (n=555),
    • Cohort 2: women aged ≥30 years who enrolled in the Mayo Clinic Biobank (n=1816),
    • Cohort 3: women aged ≥35 years seen at the Mayo Clinic for mammography (n=1534).
  • History of tubal ligation compared with age at natural menopause.
  • Funding: NIH.

Limitations

  • Relied on self-reporting for age of menopause.
  • Women with salpingectomies for reasons other than sterilization included.

Please confirm your acceptance

To gain full access to GPnotebook please confirm:

By submitting here you confirm that you have accepted Terms of Use and Privacy Policy of GPnotebook.

Submit