Weight decrease in obesity is linked to reduced migraine symptoms

  • Di Vincenzo A & al.
  • Obes Surg
  • 1 Feb 2020

  • curated by Kelli Whitlock Burton
  • Clinical Essentials
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Takeaway

  • Weight loss was associated in this meta-analysis with a significant decrease in migraine frequency, pain, disability, and duration in people with obesity.
  • Effect seen regardless of how much weight was lost or the method used.

Why this matters

  • Research suggests a link between obesity and migraine, but data on how weight loss affects migraine patterns are lacking.

Study design

  • Meta-analysis of 10 studies.
  • Outcome: headache frequency, pain severity, disability, and attack duration.
  • Funding: University of Padova.

Key results

  • Weight loss showed significant reductions in:
    • Headache frequency (P<.0001>
    • Pain severity (P<.0001>
    • Disability (P<.0001>
    • Attack duration (P=.017).
  • Pain severity was higher in the pediatric population vs adults (P=.041)

Limitations

  • Small number of studies and patients.
  • Lack of control group.