Yogurt may reduce colon cancer risk in men

  • Zheng X & al.
  • Gut
  • 17 Jun 2019

  • curated by Jim Kling
  • Univadis Clinical Summaries
Access to the full content of this site is available only to registered healthcare professionals. Access to the full content of this site is available only to registered healthcare professionals.

Takeaway

  • Yogurt consumption is tied to a lower risk for precancercous bowel lesions in men, but not women. 

Why this matters

  • The study is the first to look at associations between yogurt intake and precursors of colon cancer.

Study design

  • Prospective study of 32,606 men in the Health Professionals Follow-up Study and 55,743 women in the Nurses' Health Study with lower endoscopies performed between 1986 and 2012.
  • Funding: Various nonindustry sources.

Key results

  • There were 5811 adenomas among males and 8116 among females.
  • Men who consumed ≥2 servings of yogurt weekly had a lower risk for conventional adenomas (OR, 0.81; Ptrend=.01), and the association was stronger for adenomas with high malignant potential (OR, 0.74; Ptrend=.01).
    • The association was strong for colon adenomas (OR, 0.82; Ptrend=.01) and nonsignificant for rectal adenomas (Ptrend=.95).
    • No association with serrated lesions overall, but lower risk for lesions ≥1 cm was observed (OR, 0.48; Ptrend=.04).
  • There were no associations between yogurt consumption and adenoma risk in women.

Limitations

  • Observational design.

Please confirm your acceptance

To gain full access to GPnotebook please confirm:

By submitting here you confirm that you have accepted Terms of Use and Privacy Policy of GPnotebook.

Submit