- Yogurt consumption is tied to a lower risk for precancercous bowel lesions in men, but not women.
Why this matters
- The study is the first to look at associations between yogurt intake and precursors of colon cancer.
- Prospective study of 32,606 men in the Health Professionals Follow-up Study and 55,743 women in the Nurses' Health Study with lower endoscopies performed between 1986 and 2012.
- Funding: Various nonindustry sources.
- There were 5811 adenomas among males and 8116 among females.
- Men who consumed ≥2 servings of yogurt weekly had a lower risk for conventional adenomas (OR, 0.81; Ptrend=.01), and the association was stronger for adenomas with high malignant potential (OR, 0.74; Ptrend=.01).
- The association was strong for colon adenomas (OR, 0.82; Ptrend=.01) and nonsignificant for rectal adenomas (Ptrend=.95).
- No association with serrated lesions overall, but lower risk for lesions ≥1 cm was observed (OR, 0.48; Ptrend=.04).
- There were no associations between yogurt consumption and adenoma risk in women.
- Observational design.